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Meningitis B (MenB) Vaccination
Meningococcal disease is a serious infection caused by the bacteria Neisseria meningitides that can cause meningitis and in some cases severe septicaemia. Meningococcal disease is a significant public health problem in some parts of the world.
• Meningococcal infection is transmitted through droplet/aerosol spread of nasal/thriat secretions of infected individuals or asymptomatic carriers.
• Close/prolonged contact is required for transmission – e.g. kissing, sneezing/coughing, living in close quarters (such as a dormitory) or sharing eating and drinking utensils.
• Can be commensal of upper respiratory tract.
PRICE: Adult £140 Child £140
There is a worldwide distribution but the epidemiology of the 6 main serogroups (A, B, C, W-135, X, Y) varies geographically and over time:
The epidemic strains A and W-135 predominate in the meningitis belt of sub-Saharan Africa:
• recently outbreaks have extended out of traditional areas
• annual epidemics occur towards end of dry season
• incidence variable – 10-25 per 100,000 per annum, increasing up to a hundred fold every 5-10 years
• serogroups B and C predominate in industrialised countries – occur as sporadic cases/institutional outbreaks
o incidence 0.2-1 per 100,000 per annum
o globally highest incidence in children under 5 and older teenagers
• Incubation – 2-10 days.
• Illness – rapidly progressive over hours/days.
• Convalescence – 20% may have permanent sequelae
• Risk of severe illness
• Invasive disease may lead to bacteraemia, meningitis or septicaemia.
• Meningococcal sepsis most severe form leading to rash, persistent shock, clotting issues and multiorgan failure.
• Untreated mortality rate 70 – 90%.
• Treated mortality rate ~ 10% in industrialised world.
Signs and symptoms of meningitis
Asymptomatic carriage is possible. Symptoms commonly include one or more of the following:
• Sudden onset of fever.
• Intense headache.
• Neck stiffness.
• Rash – petechial (doesn’t blanch on pressure) – characteristic of invasive meningococcal disease, seen in up to 80% cases.
• Microscopy/Culture of CSF demonstrating causative organisms gold standard of diagnosis in UK.
• Clinical diagnosis in many regions of the world.
This is a medical emergency – intravenous or intramuscular antibiotic therapy should be given as soon as the diagnosis is suspected:
• benzylpenicillin/cefotaxime administered pre-hospital
• I.M. chloramphenicol/ceftriaxone often used as a single dose during epidemics in Africa
• close contacts treated with prophylactic antibiotics (rifampicin/ciprofloxacin).
Advice to Travellers
Vaccination should be considered under the following circumstances and is dependent on the individual risk assessment:
• Travel to region with a current outbreak/ongoing epidemic where close, prolonged contact with local population anticipated particularly in overcrowded areas.
• Travel to a high endemic region for individuals with immunodeficiency including those with no spleen
• Travel to the Hajj and Umrah pilgrimage; Note that a certificate of vaccination is required for such pilgrims.
Meningitis vaccination – what happens?
Different Meningitis vaccinations are available for different species of meningitis and different schedules also exist so the number of vaccinations required will also vary – please contact our experienced practice nurse at Glasgow Medical Rooms for further advice on the Meningitis B vaccination.
“I have had persistent neck and shoulder discomfort for some time. Regular visits to my local GP did not help. I was recommended to see Dr Sheila O’Neil who gave me a check-up and recommended that I see her physiotherapist colleague, Vicky Graham. I have had three sessions of physiotherapy and have regained full mobility in my neck and shoulders and feel a great deal better. I am very grateful to Dr Sheila and expect, with my husband, to sign up with her as regular patients.”Mrs Johnston
I would like to thank Dr O’Neill very much for her time today: I get the impression that she is a very caring professional, knowledgeable and reassuring, and that she makes explaining conditions crystal clear, which is exactly what is needed for an anxious patient like myself. The staff that I met were all extremely welcoming, well-groomed and helpful too. Add to this the very relaxing and beautifully scented ambience and it was really a truly positive and pleasant visit. Thank you.Linnea Blair
“Dr. Sheila O’Neill and her team quite literally saved my life. I cannot recommend them highly enough. Diagnosis of a serious condition that had been misdiagnosed by three hospitals took less than 2 weeks, including an MRI. Setting aside the professionalism, they are also just extremely nice people. Imagine a GP that truly cares and will be calling the patient after hours to see how they are getting on – that is what I got from Dr. Sheila O’Neill. There are no superlatives that adequately describe the service. Great. Fantastic. Superb.”GMK Group